Effects of substrate structure on the kinetics of circle opening reactions of the self-splicing intervening sequence from Tetrahymena thermophila: evidence for substrate and Mg2+ binding interactions.

The self-splicing intervening sequence from the precursor rRNA of Tetrahymena thermophila cyclizes to form a covalently closed circle. This circle can be reopened by reaction with oligonucleotides or water. The kinetics of circle opening as a function of substrate and Mg2+ concentrations have been m...

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Detalhes bibliográficos
Main Authors: Sugimoto, N, Tomka, M, Kierzek, R, Bevilacqua, P C, Turner, D H
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC331555/
https://ncbi.nlm.nih.gov/pubmed/2643083
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https://ncbi.nlm.nih.gov/pmc/articles/PMC331555/
https://ncbi.nlm.nih.gov/pubmed/2643083