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GPS-ARM: Computational Analysis of the APC/C Recognition Motif by Predicting D-Boxes and KEN-Boxes

Anaphase-promoting complex/cyclosome (APC/C), an E3 ubiquitin ligase incorporated with Cdh1 and/or Cdc20 recognizes and interacts with specific substrates, and faithfully orchestrates the proper cell cycle events by targeting proteins for proteasomal degradation. Experimental identification of APC/C...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Zexian, Yuan, Fang, Ren, Jian, Cao, Jun, Zhou, Yanhong, Yang, Qing, Xue, Yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315528/
https://ncbi.nlm.nih.gov/pubmed/22479614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034370
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