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Efficient large-scale protein sequence comparison and gene matching to identify orthologs and co-orthologs

Broadly, computational approaches for ortholog assignment is a three steps process: (i) identify all putative homologs between the genomes, (ii) identify gene anchors and (iii) link anchors to identify best gene matches given their order and context. In this article, we engineer two methods to impro...

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Hlavní autoři: Mahmood, Khalid, Webb, Geoffrey I., Song, Jiangning, Whisstock, James C., Konagurthu, Arun S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315314/
https://ncbi.nlm.nih.gov/pubmed/22210858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1261
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