The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes

Recent genome-wide association studies (GWAS) have identified a number of novel genetic associations with complex human diseases. In spite of these successes, results from GWAS generally explain only a small proportion of disease heritability, an observation termed the ‘missing heritability problem’...

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Bibliografske podrobnosti
Main Authors: Cusanovich, Darren A., Billstrand, Christine, Zhou, Xiang, Chavarria, Claudia, De Leon, Sherryl, Michelini, Katelyn, Pai, Athma A., Ober, Carole, Gilad, Yoav
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Association Studies Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315207/
https://ncbi.nlm.nih.gov/pubmed/22286170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds021
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