Negative Reward Signals from the Lateral Habenula to Dopamine Neurons Are Mediated by Rostromedial Tegmental Nucleus in Primates

Lateral habenula (LHb) neurons signal negative “reward-prediction errors” and inhibit midbrain dopamine (DA) neurons. Yet LHb neurons are largely glutamatergic, indicating that this inhibition may occur through an intermediate structure. Recent studies in rats have suggested a candidate for this rol...

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Bibliographic Details
Main Authors: Hong, Simon, Jhou, Thomas C., Smith, Mitchell, Saleem, Kadharbatcha S., Hikosaka, Okihide
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315151/
https://ncbi.nlm.nih.gov/pubmed/21832176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1384-11.2011
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