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The voltage dependence of the TMEM16B/anoctamin2 calcium-activated chloride channel is modified by mutations in the first putative intracellular loop

Ca(2+)-activated Cl(−) channels (CaCCs) are involved in several physiological processes. Recently, TMEM16A/anoctamin1 and TMEM16B/anoctamin2 have been shown to function as CaCCs, but very little information is available on the structure–function relations of these channels. TMEM16B is expressed in t...

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Autors principals: Cenedese, Valentina, Betto, Giulia, Celsi, Fulvio, Cherian, O. Lijo, Pifferi, Simone, Menini, Anna
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315145/
https://ncbi.nlm.nih.gov/pubmed/22412191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110764
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