The intestinal anti-inflammatory effect of dersalazine sodium is related to a down-regulation in IL-17 production in experimental models of rodent colitis

BACKGROUND AND PURPOSE: Dersalazine sodium (DS) is a new chemical entity formed by combining, through an azo bond, a potent platelet activating factor (PAF) antagonist (UR-12715) with 5-aminosalicylic acid (5-ASA). DS has been demonstrated to have anti-inflammatory effects on trinitrobenzene sulphon...

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Detalhes bibliográficos
Main Authors: Camuesco, D, Rodríguez-Cabezas, ME, Garrido-Mesa, N, Cueto-Sola, M, Bailón, E, Comalada, M, Arribas, B, Merlos, M, Balsa, D, Zarzuelo, A, Janer, G, Xaus, J, Román, J, Gálvez, J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315044/
https://ncbi.nlm.nih.gov/pubmed/21790535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01598.x
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