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Targeting Mutant BRAF in Melanoma: Current Status and Future Development of Combination Therapy Strategies

The discovery of activating BRAF mutations in ~50% of all melanomas has proved to be a turning point in the therapeutic management of the disseminated disease. In this commentary we review the latest research delineating the role of mutant BRAF in melanoma initiation and progression and discuss the...

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Bibliografische gegevens
Hoofdauteurs: Kudchadkar, Ragini, Paraiso, Kim H. T., Smalley, Keiran S. M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314865/
https://ncbi.nlm.nih.gov/pubmed/22453012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0b013e31824b436e
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