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Targeting Mutant BRAF in Melanoma: Current Status and Future Development of Combination Therapy Strategies
The discovery of activating BRAF mutations in ~50% of all melanomas has proved to be a turning point in the therapeutic management of the disseminated disease. In this commentary we review the latest research delineating the role of mutant BRAF in melanoma initiation and progression and discuss the...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314865/ https://ncbi.nlm.nih.gov/pubmed/22453012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0b013e31824b436e |
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