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Frequency distribution of the amide-I vibration sorted by residues in Amyloid fibrils revealed by 2D-IR measurements and simulations
The infrared optical response of Amyloid Fibrils Aβ(1–40) is investigated. Simulations of two models corresponding to different protonation states are compared with experiment. The simulations reveal that vibrational frequency distributions inside the fibrils are dominated by sidechain fluctuations....
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314731/ https://ncbi.nlm.nih.gov/pubmed/22338639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp2096423 |
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