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Pyruvate Protects Brain Against Ischemia-Reperfusion Injury by Activating Erythropoietin Signaling Pathway

BACKGROUND AND PURPOSE: Pyruvate is known to be cytoprotective through antioxidant and anti-inflammatory mechanisms. We tested the hypothesis that pyruvate protects brain against ischemia-reperfusion injury by inducing endogenous erythropoietin (EPO) expression. METHODS: Pyruvate’s protective effect...

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書誌詳細
主要な著者: Ryou, Myoung-Gwi, Liu, Ran, Ren, Ming, Sun, Jie, Mallet, Robert T., Yang, Shao-Hua
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314723/
https://ncbi.nlm.nih.gov/pubmed/22282883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.620088
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