Prediction of Muscle Energy States at Low Metabolic Rates Requires Feedback Control of Mitochondrial Respiratory Chain Activity by Inorganic Phosphate

The regulation of the 100-fold dynamic range of mitochondrial ATP synthesis flux in skeletal muscle was investigated. Hypotheses of key control mechanisms were included in a biophysical model of oxidative phosphorylation and tested against metabolite dynamics recorded by (31)P nuclear magnetic reson...

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Bibliografski detalji
Glavni autori: Schmitz, Joep P. J., Jeneson, Jeroen A. L., van Oorschot, Joep W. M., Prompers, Jeanine J., Nicolay, Klaas, Hilbers, Peter A. J., van Riel, Natal A. W.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314597/
https://ncbi.nlm.nih.gov/pubmed/22470528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034118
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