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Peptidyl 3-Hydroxyproline-Binding Properties of Type I Collagen Suggest a Function in Fibril Supramolecular Assembly

Proline residues in collagens are extensively hydroxylated post-translationally. A rare form of this modification, 3S, 2S-L-hydroxyproline (3Hyp), remains without a clear function. Disruption of the enzyme complex responsible for prolyl 3-hydroxylation results in severe forms of recessive osteogenes...

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Detalhes bibliográficos
Main Authors: Hudson, David M., Kim, Lammy S., Weis, MaryAnn, Cohn, Daniel H., Eyre, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314591/
https://ncbi.nlm.nih.gov/pubmed/22380708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2019139
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