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Naïve human T cells are activated and proliferate in response to the heme oxygenase-1 (HO-1) inhibitor tin mesoporphyrin

Heme oxygenase-1 (HO-1) and its catabolic byproducts have potent anti-inflammatory activity in many models of disease. It is not known, however, if HO-1 also plays a role in the homeostatic control of T cell activation and proliferation. We demonstrate here that the HO-1 inhibitor, tin mesoporphyrin...

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Autors principals: Burt, Trevor D., Seu, Lillian, Mold, Jeffrey E., Kappas, Attallah, McCune, Joseph M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314532/
https://ncbi.nlm.nih.gov/pubmed/20921523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903127
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