c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains

Many bacterial pathogens inject into host cells effector proteins that are substrates for host tyrosine kinases such as Src and Abl family kinases. Phosphorylated effectors eventually subvert host cell signaling, aiding disease development. In the case of the gastric pathogen Helicobacter pylori, wh...

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Autors principals: Mueller, Doreen, Tegtmeyer, Nicole, Brandt, Sabine, Yamaoka, Yoshio, De Poire, Eimear, Sgouras, Dionyssios, Wessler, Silja, Torres, Javier, Smolka, Adam, Backert, Steffen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314471/
https://ncbi.nlm.nih.gov/pubmed/22378042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61143
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