EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors

Epstein-Barr virus (EBV) persistently infects more than 90% of the human population and is etiologically linked to several B cell malignancies, including Burkitt lymphoma (BL), Hodgkin lymphoma (HL), and diffuse large B cell lymphoma (DLBCL). Despite its growth transforming properties, most immune-c...

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Bibliografiske detaljer
Main Authors: White, Robert E., Rämer, Patrick C., Naresh, Kikkeri N., Meixlsperger, Sonja, Pinaud, Laurie, Rooney, Cliona, Savoldo, Barbara, Coutinho, Rita, Bödör, Csaba, Gribben, John, Ibrahim, Hazem A., Bower, Mark, Nourse, Jamie P., Gandhi, Maher K., Middeldorp, Jaap, Cader, Fathima Z., Murray, Paul, Münz, Christian, Allday, Martin J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314448/
https://ncbi.nlm.nih.gov/pubmed/22406538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58092
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