Evidence for a stepwise program of extrathymic T cell development within the human tonsil

The development of a broad repertoire of T cells, which is essential for effective immune function, occurs in the thymus. Although some data suggest that T cell development can occur extrathymically, many researchers remain skeptical that extrathymic T cell development has an important role in gener...

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Autores principales: McClory, Susan, Hughes, Tiffany, Freud, Aharon G., Briercheck, Edward L., Martin, Chelsea, Trimboli, Anthony J., Yu, Jianhua, Zhang, Xiaoli, Leone, Gustavo, Nuovo, Gerard, Caligiuri, Michael A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314444/
https://ncbi.nlm.nih.gov/pubmed/22378041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46125
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