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Purification of a HeLa cell nuclear protein that binds selectively to DNA irradiated with ultra-violet light.
Ultraviolet (UV) light induces a variety of lesions in DNA of which the pyrimidine dimer represents the major species. Pyrimidine dimers exist as both a cyclobutane type and a 6-4' (pyrimidine-2'-one) photoproduct. We have purified a protein of M(r) approximately 125,000 from HeLa cell nuc...
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Main Authors: | , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
1993
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Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC331437/ https://ncbi.nlm.nih.gov/pubmed/8346019 |
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