Glucagon-Like Peptide 1 Recruits Microvasculature and Increases Glucose Use in Muscle via a Nitric Oxide–Dependent Mechanism

Glucagon-like peptide 1 (GLP-1) increases tissue glucose uptake and causes vasodilation independent of insulin. We examined the effect of GLP-1 on muscle microvasculature and glucose uptake. After confirming that GLP-1 potently stimulates nitric oxide (NO) synthase (NOS) phosphorylation in endotheli...

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Detalhes bibliográficos
Main Authors: Chai, Weidong, Dong, Zhenhua, Wang, Nasui, Wang, Wenhui, Tao, Lijian, Cao, Wenhong, Liu, Zhenqi
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314347/
https://ncbi.nlm.nih.gov/pubmed/22357961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1073
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