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An Alu element retroposition in two families with Huntington disease defines a new active Alu subfamily.

Alu repetitive elements represent the most common short interspersed elements (SINEs) found in primates, with an estimated 500,000 members in the haploid human genome. Considerable evidence has accumulated that these elements have dispersed in the genome by active transcription followed by retroposi...

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Bibliographic Details
Main Authors: Hutchinson, G B, Andrew, S E, McDonald, H, Goldberg, Y P, Graham, R, Rommens, J M, Hayden, M R
Format: Artigo
Language:Inglês
Published: 1993
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC331434/
https://ncbi.nlm.nih.gov/pubmed/8393987
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