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A transgenic, mesodermal specific, DKK1 mouse model recapitulates a spectrum of human congenital limb reduction defects
Congenital limb reduction defects occurring in isolation of other developmental abnormalities continue to be an important medical problem in which little progress has been made. Herein we generated transgenic mice expressing Dkk1 in an appendicular mesodermal pattern. Prx1-Dkk1 mice recapitulate a f...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314161/ https://ncbi.nlm.nih.gov/pubmed/22406973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diff.2012.01.001 |
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