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A New Branch on the Tree: Next-Generation Sequencing in the Study of Cancer Evolution
Cancer is a disease caused by the accumulation of genetic alterations in association with successive waves of clonal expansion. Mapping of the human genome sequence, in conjunction with technical advances in the ability to sequence entire genomes, have provided new insight into the mutational spectr...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314157/ https://ncbi.nlm.nih.gov/pubmed/22245832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2011.12.008 |
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