In Vivo Targeting and Imaging of Tumor Vasculature with Radiolabeled, Antibody-Conjugated Nano-Graphene

Herein we demonstrate that nano-graphene can be specifically directed to the tumor neovasculature in vivo through targeting of CD105 (i.e. endoglin), a vascular marker for tumor angiogenesis. The covalently functionalized nano-graphene oxide (GO) exhibited excellent stability and target specificity....

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Autores principales: Hong, Hao, Yang, Kai, Zhang, Yin, Engle, Jonathan W., Feng, Liangzhu, Yang, Yunan, Nayak, Tapas R., Goel, Shreya, Bean, Jero, Theuer, Charles P., Barnhart, Todd E., Liu, Zhuang, Cai, Weibo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314116/
https://ncbi.nlm.nih.gov/pubmed/22339280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn204625e
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