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The sigma-1 receptor protects against cellular oxidative stress and activates antioxidant response elements
Sigma-1 receptors are associated with Alzheimer's disease, major depressive disorders, and schizophrenia. These receptors show progrowth/antiapoptotic properties via their chaperoning functions to counteract ER (endoplasmic reticulum) stress, to block neurodegeneration, and to regulate neuritog...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314091/ https://ncbi.nlm.nih.gov/pubmed/22381068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.01.030 |
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