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Sucrose density gradient centrifugation and cross-flow filtration methods for the production of arbovirus antigens inactivated by binary ethylenimine

BACKGROUND: Sucrose density gradient centrifugation and cross-flow filtration methods have been developed and standardised for the safe and reproducible production of inactivated arbovirus antigens which are appropriate for use in diagnostic serological applications. METHODS: To optimise the maximum...

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Autors principals: Pyke, Alyssa T, Phillips, Debra A, Chuan, Teck F, Smith, Greg A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC331405/
https://ncbi.nlm.nih.gov/pubmed/14720306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-4-3
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