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A Pilot Study on Developing Mucosal Vaccine against Alveolar Echinococcosis (AE) Using Recombinant Tetraspanin 3: Vaccine Efficacy and Immunology

BACKGROUND: We have previously evaluated the vaccine efficacies of seven tetraspanins of Echinococcus multilocularis (Em-TSP1–7) against alveolar echinococcosis (AE) by subcutaneous (s.c.) administration with Freund's adjuvant. Over 85% of liver cyst lesion number reductions (CLNR) were achieve...

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Hlavní autoři: Dang, Zhisheng, Yagi, Kinpei, Oku, Yuzaburo, Kouguchi, Hirokazu, Kajino, Kiichi, Matsumoto, Jun, Nakao, Ryo, Wakaguri, Hiroyuki, Toyoda, Atsushi, Yin, Hong, Sugimoto, Chihiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313938/
https://ncbi.nlm.nih.gov/pubmed/22479658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001570
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