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Impaired neural development in a zebrafish model for Lowe syndrome
Lowe syndrome, which is characterized by defects in the central nervous system, eyes and kidneys, is caused by mutation of the phosphoinositide 5-phosphatase OCRL1. The mechanisms by which loss of OCRL1 leads to the phenotypic manifestations of Lowe syndrome are currently unclear, in part, owing to...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3313792/ https://ncbi.nlm.nih.gov/pubmed/22210625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr608 |
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