Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer

We conducted a genome-wide association study on 969 bladder cancer cases and 957 controls from Texas. For fast-track validation, we evaluated 60 SNPs in three additional US populations and validated the top SNP in nine European populations. A missense variant (rs2294008) in the PSCA gene showed cons...

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Autores principales: Wu, Xifeng, Ye, Yuanqing, Kiemeney, Lambertus A, Sulem, Patrick, Rafnar, Thorunn, Matullo, Giuseppe, Seminara, Daniela, Yoshida, Teruhiko, Saeki, Norihisa, Andrew, Angeline S, Dinney, Colin P, Czerniak, Bogdan, Zhang, Zuo-feng, Kiltie, Anne E, Bishop, D Timothy, Vineis, Paolo, Porru, Stefano, Buntinx, Frank, Kellen, Eliane, Zeegers, Maurice P, Kumar, Rajiv, Rudnai, Peter, Gurzau, Eugene, Koppova, Kvetoslava, Mayordomo, Jose Ignacio, Sanchez, Manuel, Saez, Berta, Lindblom, Annika, de Verdier, Petra, Steineck, Gunnar, Mills, Gordon B, Schned, Alan, Guarrera, Simonetta, Polidoro, Silvia, Chang, Shen-Chih, Lin, Jie, Chang, David W, Hale, Katherine S, Majewski, Tadeusz, Grossman, H Barton, Thorlacius, Steinunn, Thorsteinsdottir, Unnur, Aben, Katja K H, Witjes, J Alfred, Stefansson, Kari, Amos, Christopher I, Karagas, Margaret R, Gu, Jian
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313685/
https://ncbi.nlm.nih.gov/pubmed/19648920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.421
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