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S-allylmercaptocysteine reduces carbon tetrachloride-induced hepatic oxidative stress and necroinflammation via nuclear factor kappa B-dependent pathways in mice

PURPOSE: To study the protective effects and underlying molecular mechanisms of SAMC on carbon tetrachloride (CCl(4))-induced acute hepatotoxicity in the mouse model. METHODS: Mice were intraperitoneally injected with CCl(4) (50 μl/kg; single dose) to induce acute hepatotoxicity with or without a 2-...

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Detalhes bibliográficos
Main Authors: Xiao, Jia, Liong, Emily C., Ling, Ming-Tat, Ching, Yick-Pang, Fung, Man-Lung, Tipoe, George L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313023/
https://ncbi.nlm.nih.gov/pubmed/21681437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00394-011-0217-0
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