A large scale multivariate parallel ICA method reveals novel imaging-genetic relationships for Alzheimer’s Disease in the ADNI cohort

The underlying genetic etiology of late onset Alzheimer’s disease (LOAD) remains largely unknown, likely due to its polygenic architecture and a lack of sophisticated analytic methods to evaluate complex genotype-phenotype models. The aim of the current study was to overcome these limitations in a b...

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Auteurs principaux: Meda, Shashwath A, Narayanan, Balaji, Liu, Jingyu, Perrone-Bizzozero, Nora I., Stevens, Michael C., Calhoun, Vince D., Glahn, David C., Shen, Li, Risacher, Shannon L., Saykin, Andrew J., Pearlson, Godfrey D.
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312985/
https://ncbi.nlm.nih.gov/pubmed/22245343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2011.12.076
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