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Impact of hemochromatosis gene (HFE) mutations on epithelial ovarian cancer risk and prognosis

Cancer cells require large amounts of micronutrients, particularly iron, for their rapid growth and frequent divisions. Cellular iron uptake is regulated by the transferrin receptor and the hemochromatosis protein (HFE) system. Two frequent mutations in the HFE gene, H63D and C282Y, are associated w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gannon, Philippe O., Medelci, Sanae, Le Page, Cécile, Beaulieu, Martin, Provencher, Diane M., Mes-Masson, Anne-Marie, Santos, Manuela M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312916/
https://ncbi.nlm.nih.gov/pubmed/20669231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25577
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