FOXM1 Induces a Global Methylation Signature That Mimics the Cancer Epigenome in Head and Neck Squamous Cell Carcinoma

The oncogene FOXM1 has been implicated in all major types of human cancer. We recently showed that aberrant FOXM1 expression causes stem cell compartment expansion resulting in the initiation of hyperplasia. We have previously shown that FOXM1 regulates HELLS, a SNF2/helicase involved in DNA methyla...

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Main Authors: Teh, Muy-Teck, Gemenetzidis, Emilios, Patel, Deeviyaben, Tariq, Rameez, Nadir, Ayesha, Bahta, Adiam W., Waseem, Ahmad, Hutchison, Iain L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312909/
https://ncbi.nlm.nih.gov/pubmed/22461910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034329
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