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Clinical decision support of therapeutic drug monitoring of phenytoin: measured versus adjusted phenytoin plasma concentrations

BACKGROUND: Therapeutic drug monitoring of phenytoin by measurement of plasma concentrations is often employed to optimize clinical efficacy while avoiding adverse effects. This is most commonly accomplished by measurement of total phenytoin plasma concentrations. However, total phenytoin levels can...

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Detalhes bibliográficos
Main Authors: Krasowski, Matthew D, Penrod, Louis E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312854/
https://ncbi.nlm.nih.gov/pubmed/22333264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6947-12-7
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