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The carboxyl-terminal part of the putative Berne virus polymerase is expressed by ribosomal frameshifting and contains sequence motifs which indicate that toro- and coronaviruses are evolutionarily related.

Sequence analysis of the 3' part (8 kb) of the polymerase gene of the torovirus prototype Berne virus (BEV) revealed that this area contains at least two open reading frames (provisionally designated ORF1a and ORF1b) which overlap by 12 nucleotides. The complete sequence of ORF1b (6873 nucleoti...

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Main Authors: Snijder, E J, den Boon, J A, Bredenbeek, P J, Horzinek, M C, Rijnbrand, R, Spaan, W J
格式: Artigo
語言:Inglês
出版: 1990
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC331274/
https://ncbi.nlm.nih.gov/pubmed/2388833
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