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The crucial role of PNPase in the degradation of small RNAs that are not associated with Hfq

The transient existence of small RNAs free of binding to the RNA chaperone Hfq is part of the normal dynamic lifecycle of a sRNA. Small RNAs are extremely labile when not associated with Hfq, but the mechanism by which Hfq stabilizes sRNAs has been elusive. In this work we have found that polynucleo...

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Autors principals: Andrade, José M., Pobre, Vânia, Matos, Ana M., Arraiano, Cecília M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312570/
https://ncbi.nlm.nih.gov/pubmed/22355164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.029413.111
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