Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles

MALAT-1 noncoding RNA is localized to nuclear speckles despite its mRNA-like characteristics. Here, we report the identification of several key factors that promote the localization of MALAT-1 to nuclear speckles and also provide evidence that MALAT-1 is involved in the regulation of gene expression...

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Detalhes bibliográficos
Main Authors: Miyagawa, Ryu, Tano, Keiko, Mizuno, Rie, Nakamura, Yo, Ijiri, Kenichi, Rakwal, Randeep, Shibato, Junko, Masuo, Yoshinori, Mayeda, Akila, Hirose, Tetsuro, Akimitsu, Nobuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312561/
https://ncbi.nlm.nih.gov/pubmed/22355166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.028639.111
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