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Specificity of binding to four-way junctions in DNA by bacteriophage T7 endonuclease I.
T7 endonuclease I binds specifically to four-way junctions in duplex DNA and promotes their resolution into linear duplexes. Under conditions in which the nuclease activity is blocked by the absence of divalent cations, the enzyme forms a distinct protein-DNA complex with the junction, as detected b...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1990
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC331254/ https://ncbi.nlm.nih.gov/pubmed/2167465 |
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