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Specificity of binding to four-way junctions in DNA by bacteriophage T7 endonuclease I.

T7 endonuclease I binds specifically to four-way junctions in duplex DNA and promotes their resolution into linear duplexes. Under conditions in which the nuclease activity is blocked by the absence of divalent cations, the enzyme forms a distinct protein-DNA complex with the junction, as detected b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Parsons, C A, West, S C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC331254/
https://ncbi.nlm.nih.gov/pubmed/2167465
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