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Biotinyl and phosphotyrosinyl phosphoramidite derivatives useful in the incorporation of multiple reporter groups on synthetic oligonucleotides.

Non-nucleosidic phosphoramidite linker units suitable for use on commercial DNA synthesis machines have been designed for the direct incorporation of biotin and a new reporter group, phosphotyrosine, at multiple sites on synthetic oligonucleotides. The units are based on a 3-carbon glyceryl backbone...

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Bibliografiske detaljer
Main Authors: Misiura, K, Durrant, I, Evans, M R, Gait, M J
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC331250/
https://ncbi.nlm.nih.gov/pubmed/1697061
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