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Chronic blockade of cannabinoid CB(2) receptors induces anxiolytic-like actions associated with alterations in GABA(A) receptors

BACKGROUND AND PURPOSE: The aim of this study was to explore the effects of CB(2) receptor agonist and antagonist in the regulation of anxiety-like behaviours. EXPERIMENTAL APPROACHES: Effects of acute and chronic treatment with the CB(2) receptor agonist JWH133 and CB(2) receptor antagonist AM630 w...

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Detalhes bibliográficos
Main Authors: García-Gutiérrez, María S, García-Bueno, Borja, Zoppi, Silvia, Leza, Juan C, Manzanares, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312491/
https://ncbi.nlm.nih.gov/pubmed/21838753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01625.x
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