Meta-analysis of Gene-Environment interaction: joint estimation of SNP and SNP×Environment regression coefficients

INTRODUCTION: Genetic discoveries are validated through the meta-analysis of genome-wide association scans in large international consortia. Because environmental variables may interact with genetic factors, investigation of differing genetic effects for distinct levels of an environmental exposure...

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Main Authors: Manning, Alisa K., LaValley, Michael, Liu, Ching-Ti, Rice, Ken, An, Ping, Liu, Yongmei, Miljkovic, Iva, Rasmussen-Torvik, Laura, Harris, Tamara B., Province, Michael A., Borecki, Ingrid B., Florez, Jose C., Meigs, James B., Cupples, L. Adrienne, Dupuis, Josée
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312394/
https://ncbi.nlm.nih.gov/pubmed/21181894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20546
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