Measurements of single DNA molecule packaging dynamics in bacteriophage λ reveal high forces, high motor processivity, and capsid transformations

Molecular motors drive genome packaging into preformed procapsids in many dsDNA viruses. Here, we present optical tweezers measurements of single DNA molecule packaging in bacteriophage λ. DNA-gpA-gpNu1 complexes were assembled with recombinant gpA and gpNu1 proteins and tethered to microspheres, an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fuller, Derek N., Raymer, Dorian M., Rickgauer, John Peter, Robertson, Rae M., Catalano, Carlos E., Anderson, Dwight L., Grimes, Shelley, Smith, Douglas E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311920/
https://ncbi.nlm.nih.gov/pubmed/17919653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.09.011
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