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Isoflurane enhances both fast and slow synaptic inhibition in the hippocampus at amnestic concentrations

BACKGROUND: Inhibition mediated by γ-aminobutyric acid type A (GABA(A)) receptors has long been considered an important target for a variety of general anesthetics. In the hippocampus, two types of phasic GABA(A) receptor-mediated inhibition coexist: GABA(A,fast), which is expressed primarily at per...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dai, Shuiping, Perouansky, Misha, Pearce, Robert A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311774/
https://ncbi.nlm.nih.gov/pubmed/22343472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31824be0e3
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