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Intrapulmonary Administration of Leukotriene B(4) Augments Neutrophil Accumulation and Responses in the Lung to Klebsiella Infection in CXCL1 Knockout Mice
In prior studies we demonstrated that: 1) CXCL1/KC is essential for NF-κB and MAPK activation, and expression of CXCL2/MIP-2 and CXCL5/LPS-induced CXC chemokine in Klebsiella-infected lungs; and 2) CXCL1 derived from hematopoietic and resident cells contributes to host immunity against Klebsiella. H...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311767/ https://ncbi.nlm.nih.gov/pubmed/22379035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101985 |
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