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Maxadilan Prevents Apoptosis in iPS Cells and Shows No Effects on the Pluripotent State or Karyotype

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a structurally endogenous peptide with many biological roles. Maxadilan, a 61-amino acid vasodilatory peptide, specifically activates the PACAP type I receptor (PAC1). Although PAC1 has been identified in embryonic stem cells, little is k...

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Bibliografiske detaljer
Main Authors: Zhao, Zhiyi, Yu, Rongjie, Yang, Jiayin, Liu, Xiaofei, Tan, Meihua, Li, HongYang, Chen, Jiansu
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311553/
https://ncbi.nlm.nih.gov/pubmed/22457805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033953
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