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miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling

Chronic hypoxia causes pulmonary vascular remodeling leading to pulmonary hypertension (PH) and right ventricle (RV) hypertrophy. Aberrant expression of microRNA (miRNA) is closely associated with a number of pathophysiologic processes. However, the role of miRNAs in chronic hypoxia-induced pulmonar...

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Bibliographic Details
Main Authors: Yang, Shanzhong, Banerjee, Sami, de Freitas, Andressa, Cui, Huachun, Xie, Na, Abraham, Edward, Liu, Gang
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311531/
https://ncbi.nlm.nih.gov/pubmed/22227207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00316.2011
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