Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfide

Cinaciguat (BAY 58–2667) is a novel nitric oxide (NO)-independent activator of soluble guanylate cyclase (sGC), which induces cGMP-generation and vasodilation in diseased vessels. We tested the hypothesis that cinaciguat might trigger protection against ischemia/reperfusion (I/R) in the heart and ad...

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Bibliografische gegevens
Hoofdauteurs: Salloum, Fadi N., Das, Anindita, Samidurai, Arun, Hoke, Nicholas N., Chau, Vinh Q., Ockaili, Ramzi A., Stasch, Johannes-Peter, Kukreja, Rakesh C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2012
Onderwerpen:
Integrative Cardiovascular Physiology and Pathophysiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311478/
https://ncbi.nlm.nih.gov/pubmed/22268103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00544.2011
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