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Normal pregnancy: mechanisms underlying the paradox of a ouabain-resistant state with elevated endogenous ouabain, suppressed arterial sodium calcium exchange, and low blood pressure

Endogenous cardiotonic steroids (CTS) raise blood pressure (BP) via vascular sodium calcium exchange (NCX1.3) and transient receptor-operated channels (TRPCs). Circulating CTS are superelevated in pregnancy-induced hypertension and preeclampsia. However, their significance in normal pregnancy, where...

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Detalhes bibliográficos
Main Authors: Jacobs, Brandiese E., Liu, Yong, Pulina, Maria V., Golovina, Vera A., Hamlyn, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311474/
https://ncbi.nlm.nih.gov/pubmed/22245773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00532.2011
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