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Tetrahydrobiopterin improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women

The mechanisms mediating arterial stiffening with aging and menopause are not completely understood. We determined whether administration of tetrahydrobiopterin (BH(4)), a critical cofactor for endothelial nitric oxide synthase to produce nitric oxide, would increase vascular endothelial-dependent v...

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Detalhes bibliográficos
Main Authors: Moreau, Kerrie L., Meditz, Amie, Deane, Kevin D., Kohrt, Wendy M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311456/
https://ncbi.nlm.nih.gov/pubmed/22245769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01065.2011
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