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Interaction between uric acid and HMGB1 translocation and release from endothelial cells

We aimed to investigate the potential relationship between alarmins [acting via Toll-like receptor-4 (TLR4)], uric acid (UA), and high-mobility group box-1 protein (HMGB1) during acute kidney injury. UA, which is significantly increased in the circulation following renal ischemia-reperfusion injury...

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Detalhes bibliográficos
Main Authors: Rabadi, May M., Kuo, Mei-Chuan, Ghaly, Tammer, Rabadi, Seham M., Weber, Mia, Goligorsky, Michael S., Ratliff, Brian B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311321/
https://ncbi.nlm.nih.gov/pubmed/22189943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00520.2011
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