Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane

Vascular development and angiogenesis initially depend on endothelial tip cell invasion, which is followed by a series of maturation steps, including lumen formation and recruitment of perivascular cells. Notch ligands expressed on the endothelium and their cognate receptors expressed on perivascula...

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Detalhes bibliográficos
Main Authors: Scheppke, Lea, Murphy, Eric A., Zarpellon, Alessandro, Hofmann, Jennifer J., Merkulova, Alona, Shields, David J., Weis, Sara M., Byzova, Tatiana V., Ruggeri, Zaverio M., Iruela-Arispe, M. Luisa, Cheresh, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311249/
https://ncbi.nlm.nih.gov/pubmed/22134168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-348706
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