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Mechanisms by which TFG functions in protein secretion and oncogenesis

Export of proteins from the endoplasmic reticulum (ER) in COPII-coated vesicles occurs at defined sites, which contain the scaffolding protein Sec16. We identify TFG-1, a new conserved regulator of protein secretion that interacts directly with SEC-16 and controls the export of cargoes from the ER i...

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Bibliografske podrobnosti
Main Authors: Witte, Kristen, Schuh, Amber L., Hegermann, Jan, Sarkeshik, Ali, Mayers, Jonathan R., Schwarze, Katrin, Yates, John R., Eimer, Stefan, Audhya, Anjon
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311221/
https://ncbi.nlm.nih.gov/pubmed/21478858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2225
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